(S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate
N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M
CAS: 87694-50-6
Molecular Formula: C13H26N2O4
(S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate - Names and Identifiers
| Name | N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M |
| Synonyms | BOC-LEU-NME(OME) BOC-LEU-N(OME)ME BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE Boc-L-Leucine N,O-Dimethylhydroxamide N-Boc-L-leucine N'-Methoxy-N'-MethylaMide N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M N-(tert-Butoxycarbonyl)-L-leucine N-methoxy-N-methylamide N~2~-(tert-butoxycarbonyl)-N-methoxy-N-methyl-L-leucinamide N-(TERT-BUTOXYCARBONYL)-L-LEUCINE N'-METHOXY-N'-METHYLAMIDE (S)-N-Methyl-N-methoxy-2-(tert-butoxycarbonylamino)-4-methylpentanamide (S)-tert-butyl 1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-ylcarbamate (S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate |
| CAS | 87694-50-6 |
| InChI | InChI=1/C13H26N2O4/c1-9(2)8-10(11(16)15(6)18-7)14-12(17)19-13(3,4)5/h9-10H,8H2,1-7H3,(H,14,17)/t10-/m0/s1 |
(S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate - Physico-chemical Properties
| Molecular Formula | C13H26N2O4 |
| Molar Mass | 274.36 |
| Density | 1.46g/mLat 25°C(lit.) |
| Boling Point | 235°C(lit.) |
| Flash Point | >230°F |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.454(lit.) |
| Use | This product is for scientific research only and shall not be used for other purposes. |
(S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate - Risk and Safety
| WGK Germany | 3 |
(S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate - Introduction
N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N '-M, also known as N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M, is an organic compound.
Nature:
1. appearance: common solid, generally white crystal or crystalline powder.
2. Melting point: According to laboratory records, its melting point is between about 132-136°C.
3. molecular formula: C16H30N2O5
4. Molecular weight: 338.42g/mol
5. solubility: soluble in some organic solvents such as methanol, ethanol and dichloromethane, slightly soluble in water.
Use:
The compound is commonly used in the synthesis of amine protecting groups in organic synthesis and targeted drugs.
Preparation Method:
The method for preparing this compound can be divided into multiple reactions. The specific steps are as follows:
1. Taking tert-butyl methyl 2-carbamate and dimethyl methyl malonate, (S)-tert-butyl methyl 2-aminomethylmalonate was prepared by transesterification.
2. The compound obtained in step 1 is reacted with methanol to obtain methyl (S)-tert-butyl 2-methoxymethylmalonate.
3. The compound obtained in step 2 is reacted with 1-chloromethyl-3-methylmalonate octyl ester to produce N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N '-M.
Safety Information:
The compound is generally stable and relatively safe under normal operating conditions. But still need to pay attention to the following matters:
1. avoid contact with skin and eyes, avoid inhalation or ingestion.
2. During operation, be sure to wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
3. It should be operated in a well-ventilated laboratory environment to avoid the accumulation of harmful gases.
4. In case of contact with the compound, rinse immediately with plenty of water and seek medical attention immediately.
Please note that the above information is for reference only and specific properties, uses, manufacturing methods and safety information should rely on laboratory manuals, safety data sheets and professional guidance.
Nature:
1. appearance: common solid, generally white crystal or crystalline powder.
2. Melting point: According to laboratory records, its melting point is between about 132-136°C.
3. molecular formula: C16H30N2O5
4. Molecular weight: 338.42g/mol
5. solubility: soluble in some organic solvents such as methanol, ethanol and dichloromethane, slightly soluble in water.
Use:
The compound is commonly used in the synthesis of amine protecting groups in organic synthesis and targeted drugs.
Preparation Method:
The method for preparing this compound can be divided into multiple reactions. The specific steps are as follows:
1. Taking tert-butyl methyl 2-carbamate and dimethyl methyl malonate, (S)-tert-butyl methyl 2-aminomethylmalonate was prepared by transesterification.
2. The compound obtained in step 1 is reacted with methanol to obtain methyl (S)-tert-butyl 2-methoxymethylmalonate.
3. The compound obtained in step 2 is reacted with 1-chloromethyl-3-methylmalonate octyl ester to produce N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N '-M.
Safety Information:
The compound is generally stable and relatively safe under normal operating conditions. But still need to pay attention to the following matters:
1. avoid contact with skin and eyes, avoid inhalation or ingestion.
2. During operation, be sure to wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
3. It should be operated in a well-ventilated laboratory environment to avoid the accumulation of harmful gases.
4. In case of contact with the compound, rinse immediately with plenty of water and seek medical attention immediately.
Please note that the above information is for reference only and specific properties, uses, manufacturing methods and safety information should rely on laboratory manuals, safety data sheets and professional guidance.
Last Update：2024-04-09 15:18:00
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Product Name: BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE Visit Supplier Webpage Request for quotation
CAS: 87694-50-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 87694-50-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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